Molecular Markers in Diagnostic Paediatric Bone Lesions

Molecular pathology has become an essential adjunct in the realm of diagnostic histopathology. While gains in this field have been enjoyed in many areas, their impact has arguably been greatest felt in bone and soft tissue pathology. The purpose of this paper is to highlight the emerging role of molecular techniques in the context of paediatric bone pathology, discussing select syndromic and neoplastic processes affecting this demographic. To this end, we review the salient molecular advances bridging both clinical research and clinical practice.